“Effect of hyperbaric oxygen therapy for non-motor symptoms among patients with Parkinson’s disease: A systematic review and meta-analysis”
The effects of hyperbaric oxygen on mental health, cognition and sleep in patient’s with Parkinson’s disease were assessed in a review article published in Clinical Rehabilitation in March 2025. This meta-analysis included 16 studies and involved 1324 patients overall.
Hyperbaric oxygen therapy was found to improve scores on formal scales assessing anxiety, depression, cognition, sleep, and overall function. Although protocols varied, the use of hyperbaric oxygen proved beneficial in parkinsonian patients, improving both motor function and non-motor symptoms. [Clin Rehabil. 2025 Mar;39(3):281-294.]